The problem - Nosocomial Infections in ICU

• Pneumonia constitutes highest percentage of nosocomial infections in ICUs

       Resulting in cost increase and financial loss for the hospitals

    - Length Of Stay (LOS) and treatment of medical complications

• Ventilated Associated Pneumonia (VAP) is a major complication

    - approx. 25% of all invasive ventilated patients in China get VAP

    - approx. 30% in the USA and 40% in Germany suffer from VAP

• Current applicable prevention measures for VAP are considered to be insufficient

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Critical Care – unmet need

Current standard of care

• Patients are usually Ventilated, Sedated, on antacids and fed through a NasoGastric tube

 

Possible clinical consequences

• Peristaltic action of the oesophagus is impaired, open GE sphincter, sub-optimal ventilation, Increased bacterial risk of infection, Sub-optimal feeding

 

Patient’s infections

• Gastric fluids with bacteria travel into the patient’s  airway and reach the lungs causing infections

• 90% of enteral fed patients aspirate gastric contents

• Aspiration of gastric contents is a major risk factor of pneumonia, resulting in complications and mortality 

 

Unmet need

• Reduce the clinical consequences of the peristaltic action of the esophagus (reflux)  to diminish patient infection and AVP (Associated Ventilation Pneumonia) 

• Cost savings of $1,200 - $17,000, per ventilated patient, for full prevention of VAP

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SOLUTION

Enteral feeding Gastric Fluids Prevention Technology 

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LunGuard – The Product

• Position to become  the “standard-of-care” in enteral-fed ventilated patients

• It enhance and optimise the efficiency  and safety for both ventilation and feeding

• Reduces aspiration of gastric fluids compared to regular NG tube

• Strong IP portfolio 

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LunGuard’s Nutrition Advantage

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• KEEP GASTRIC FLUIDS IN THE STOMACH

• PROTECT THE TRACHEA AND LUNGS FROM CONTAMINATION

• PFT mimics the Peristaltic esophagus movement

• Reducing reflux clinical consequences

• Acts as a one-way valve allowing saliva secretion

• Improve trade-off between under-feeding patients and lowering aspiration risk

• Better nourished patients have better treatment outcomes at a lower cost 

• allowing feeding throughout the 24h without a night-time break due to aspiration risk

• Increases  nutrition up to 25% by allowing earlier and more efficient feeding rate in a moderated reflux environment 

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